General Hospital Psychiatry
Volume 25, Issue 5 , Pages 303-310 , September 2003

Enhancing adherence to prevent depression relapse in primary care

  • Elizabeth H.B Lin, M.D., M.P.H.

      Affiliations

    • Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
    • Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-206-287-4264; fax: +1-206-287-2871.
  • ,
  • Michael Von Korff, Sc.D.

      Affiliations

    • Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
    • Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
  • ,
  • Evette J Ludman, Ph.D.

      Affiliations

    • Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
  • ,
  • Carolyn Rutter, Ph.D.

      Affiliations

    • Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
  • ,
  • Terry M Bush, Ph.D.

      Affiliations

    • Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
  • ,
  • Gregory E Simon, M.D., M.P.H.

      Affiliations

    • Center for Health Studies, Group Health Cooperative, Seattle, WA, USA
    • Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
  • ,
  • Jürgen Unützer, M.D., M.P.H.

      Affiliations

    • University of California, Los Angeles Neuropsychiatric Institute, Los Angeles, CA, USA
  • ,
  • Edward Walker, M.D., M.P.H.

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
  • ,
  • Wayne J Katon, M.D.

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA

References 

  1. Solomon DA, Keller MB, Leon AC, Mueller TI, Lavori PW, Shea MT, et al.  Multiple recurrences of major depressive disorder. Am J Psychiatry. 2000;157(2):229–233
  2. Lin EH, Katon WJ, Simon GE, Von Korff M, Bush TM, Walker EA, et al.  Low-intensity treatment of depression in primary care (is it problematic?). Gen Hosp Psychiatry. 2000;22(2):78–83
  3. Lin EH, Katon WJ, VonKorff M, Russo JE, Simon GE, Bush TM, et al.  Relapse of depression in primary care. Rate and clinical predictors. Arch Fam Med. 1998;7(5):443–449
  4. Kupfer DJ, Frank E, Perel JM, Cornes C, Mallinger AG, Thase ME, et al.  Five-year outcome for maintenance therapies in recurrent depression. Arch Gen Psychiatry. 1992;49(10):769–773
  5. Demyttenaere K, Enzlin P, Dewe W, Boulanger B, De Bie J, De Troyer W, et al.  Compliance with antidepressants in a primary care setting (beyond lack of efficacy and adverse events). J Clin Psychiatry. 2001;62(Suppl 22):30–33
  6. Claxton A, Li X, McKendrick J. Selective serotonin reuptake inhibitor treatment in the UK (risk of relapse and recurrence of depression). Br J Psychiatry. 2000;177:163–168
  7. Public Health Service Agency for Health Care Policy and Research . Depression in Primary Care (Volume 2. Treatment of Major Depression). Rockville, MD: DHHS; 1993;
  8. Cramer JA, Rosenheck R. Compliance with medication regimens for mental and physical disorders. Psychiatr Serv. 1998;49(2):196–201
  9. Melfi CA, Chawla AJ, Croghan TW, Hanna MP, Kennedy S, Sredl K. The effects of adherence to antidepressant treatment guidelines on relapse and recurrence of depression. Arch Gen Psychiatry. 1998;55:1128–1132
  10. DiMatteo MR. Enhancing patient adherence to medical recommendations. JAMA. 1994;5:271; (1):79–83.
  11. DiMatteo MR. Patient adherence to pharmacotherapy (the importance of effective communication). Formulary. 1995;30(10):596–598 601–2, 605
  12. Katon W, Von Korff M, Lin E, Walker E, Simon GE, Bush T, et al.  Collaborative management to achieve treatment guidelines. Impact on depression in primary care. JAMA. 1995;5:273; (13):1026–1031
  13. Bultman DC, Svarstad BL. Effects of physician communication style on client medication beliefs and adherence with antidepressant treatment. Patient Educ Couns. 2000;40(2):173–185
  14. Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996;10:348; 348(9024.9024):383–386
  15. Sirey JA, Bruce ML, Alexopoulos GS, Perlick DA, Friedman SJ, Meyers BS. Stigma as a barrier to recovery (Perceived stigma and patient-rated severity of illness as predictors of antidepressant drug adherence). Psychiatr Serv. 2001;52(12):1615–1620
  16. Lin EHB, Von Korff M, Katon W, Bush T, Simon GE, Walker E, et al.  The role of the primary care physician in patients' adherence to antidepressant therapy. Med Care. 1995;33(1):67–74
  17. Rush AJ, Thase ME. Strategies and tactics in the treatment of chronic depression. J Clin Psychiatry. 1997;58(Suppl 13):14–22
  18. Kupfer DJ, Frank E. The interaction of drug- and psychotherapy in the long-term treatment of depression. J Affect Disord. 2001;62(1-2):131–137
  19. Powell KM, Edgren B. Failure of educational videotapes to improve medication compliance in a health maintenance organization. Am J Health Syst Pharm. 1995;52(20):2196–2199
  20. Mundt JC, Clarke GN, Burroughs D, Brenneman DO, Griest JH. Effectiveness of antidepressant pharmacotherapy (the impact of medication compliance and patient education). Depress Anxiety. 2001;13:1–10
  21. Bultman DC, Svarstad BL. Effects of pharmacist monitoring on patient satisfaction with antidepressant medication therapy. J Am Pharm Assoc. 2002;42(1):36–43
  22. Peveler R, George C, Kinmonth AL, Campbell M, Thompson C. Effect of antidepressant drug counselling and information leaflets on adherence to drug treatment in primary care (randomised controlled trial). BMJ. 1999;319(7210):612–615
  23. Unutzer J, Rubenstein L, Katon WJ, Tang L, Duan N, Lagomasino IT, et al.  Two-year effects of quality improvement programs on medication management for depression. Arch Gen Psychiatry. 2001;58(10):935–942
  24. Katon W, Rutter C, Ludman EJ, Von Korff M, Lin E, Simon G, et al.  A randomized trial of relapse prevention of depression in primary care. Arch Gen Psychiatry. 2001;58(3):241–247
  25. Simon GE, Von Korff M, Ludman EJ, Katon WJ, Rutter C, Unutzer J, et al.  Cost-effectiveness of a program to prevent depression relapse in primary care. Med Care. 2002;40(10):941–950
  26. Spitzer RL, Williams JB, Gibbon M, First MB. The Structured Clinical Interview for DSM-III-R (SCID). I (History, rationale, and description). Arch Gen Psychiatry. 1992;49(8):624–629
  27. Derogatis LR, Rickels K, Uhlenhuth EH, et al.  The Hopkins Symptom Checklist: a measure of primary symptom dimensions. In:  Pinchot P editors. Psychological Measurements in Psychopharmacology: Problems in Pharmacopsychiatry. Basil, Switzerland: Kargerman; 1974;
  28. Mayfield D, McLeod G, Hall P. The CAGE questionnaire (validation of a new alcoholism screening instrument). Am J Psychiatry. 1974;131(10):1121–1123
  29. Ludman E, Von Korff M, Katon W, Lin E, Simon G, Walker E, et al.  The design, implementation, and acceptance of a primary care-based intervention to prevent depression relapse. Int J Psychiatry Med. 2000;30(3):229–245
  30. Frank E, Kupfer DJ, Perel JM. Three-year outcomes for maintenance therapies in recurent depression. Arch Gen Psychiatry. 1990;47:1093–1099
  31. Cooper-Patrick L, Powe N, Jenckes M, Gonzales J, Levine D, Ford DE. Identification of patient attitudes and preferences regarding treatment of depression. JGIM. 1997;12(7):431–438
  32. Brown RA, Lewinsohn PM. A psychoeducational approach to the treatment of depression (comparison of group, individual, and minimal contact procedures). J Consult Clin Psychol. 1984;52(5):774–783
  33. Lewinsohn P, Antonuccio D, Steinmetz J, et al.  The Coping with Depression Course (A Psychoeducational Intervention for Unipolar Depression). Eugene, OR: Castalia Press; 1984;
  34. Saunders K, Simon G, Bush T, Grothaus L. Assessing the feasibility of using computerized pharmacy refill data to monitor antidepressant treatment on a population basis (a comparison of automated and self-report data). J Clin Epidemiol. 1998;51(10):883–890
  35. Katon W, Robinson P, Von Korff M, Lin E, Bush T, Ludman E, et al.  A multifaceted intervention to improve treatment of depression in primary care. Arch Gen Psychiatry. 1996;53(10):924–932
  36. Klinger L, Spaulding SJ, Polatajko HJ, MacKinnon JR, Miller L. Chronic pain in the elderly (occupational adaptation as a means of coping with osteoarthritis of the hip and/or knee). Clin J Pain. 1999;15(4):275–283
  37. Ludman EJ, Katon W, Bush T, et al.  Behavioral factors associated with symptom outcomes in a primary care-based depression prevention intervention trial. Psychol Med. 2003;33:1061–1070
  38. Diggle PJ, Liang KY, Zeger SL. Analysis of Longitudinal Data. New York: Oxford University Press; 1994;
  39. Neuhaus JM. Assessing change with longitudinal and clustered binary data. Annu Rev Public Health. 2001;22:115–128
  40. Simon GE, VonKorff M, Wagner EH, Barlow W. Patterns of antidepressant use in community practice. Gen Hosp Psychiatry. 1993;15(6):399–408
  41. Smith JL, Rost KM, Nutting PA, Elliott CE. Resolving disparities in antidepressant treatment and quality-of-life outcomes between uninsured and insured primary care patients with depression. Med Care. 2001;39(9):910–922
  42. George CF, Peveler RC, Heiliger S, Thompson C. Compliance with tricyclic antidepressants (the value of four different methods of assessment). Br J Clin Pharmacol. 2000;50(2):166–171
  43. Kwon A, Bungay KM, Pei Y, Rogers WH, Wilson IB, Zhou Q, et al.  Antidepressant use (concordance between self-report and claims records). Med Care. 2003;41(3):368–374
  44. Unutzer J, Katon W, Callahan CM, Williams JW, Hunkeler E, Harpole L, et al.  Depression treatment in a sample of 1,801 depressed older adults in primary care. J Am Geriatr Soc. 2003;51(4):505–514

PII: S0163-8343(03)00074-4

doi: 10.1016/S0163-8343(03)00074-4

General Hospital Psychiatry
Volume 25, Issue 5 , Pages 303-310 , September 2003