General Hospital Psychiatry
Volume 26, Issue 3 , Pages 237-240 , May 2004

Suicidal ideation during interferon-α2b and ribavirin treatment of patients with chronic hepatitis C

  • Eric Dieperink, M.D.

      Affiliations

    • Department of Psychiatry (116A), Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
    • Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-612-725-2000 x3964; fax: +1-612-725-2013.
    • ,
  • Samuel B. Ho, M.D.

      Affiliations

    • Department of Medicine, Veterans Affairs Medical Center, Minneapolis, MN, USA
    • Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    • ,
  • Lori Tetrick, L.P.N.

      Affiliations

    • Department of Medicine, Veterans Affairs Medical Center, Minneapolis, MN, USA
    • ,
  • Paul Thuras, Ph.D.

      Affiliations

    • Department of Psychiatry (116A), Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
    • Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA
    • ,
  • Kulwinder Dua, M.D.

      Affiliations

    • Veterans Affairs Medical Center, Milwaukee, WI, USA
    • ,
  • Mark L. Willenbring, M.D.

      Affiliations

    • Department of Psychiatry (116A), Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
    • Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA

Received 16 September 2003 ,Accepted 7 January 2004.

References 

  1. Alter MJ. Hepatitis C virus infection in the United States. J Hepatol. 1999;31(Suppl 1):88–91
  2. Nguyen HA, Miller AI, Dieperink E, et al.  Spectrum of disease in U.S. veteran patients with hepatitis C. Am J Gastroenterol. 2002;97:1813–1820
  3. el-Serag HB, Kunik M, Richardson P, Rabeneck L. Psychiatric disorders among veterans with hepatitis C infection. Gastroenterology. 2002;123:476–482
  4. Dieperink E, Willenbring M, Ho SB. Neuropsychiatric symptoms associated with hepatitis C and interferon alpha (a review). Am J Psychiatry. 2000;157:867–876
  5. Lish JD, Zimmerman M, Farber NJ, et al.  Suicide screening in a primary care setting at a Veterans Affairs Medical Center. Psychosomatics. 1996;37:413–424
  6. Dieperink E, Ho SB, Thuras P, Willenbring ML. A prospective study of neuropsychiatric symptoms associated with interferon-alpha-2b and ribavirin therapy for patients with chronic hepatitis C. Psychosomatics. 2003;44:104–112
  7. McHutchison JG, Gordon SC, Schiff ER, et al.  Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N Engl J Med. 1998;339:1485–1492
  8. Williams JB. A structured interview guide for the Hamilton Depression Rating Scale. Arch Gen Psychiatry. 1988;45:742–747
  9. Beck AT, Beamesderfer A. Assessment of depression (the depression inventory). Mod Probl Pharmacopsychiatry. 1974;7:151–169
  10. Zimmerman M, Coryell W. The Inventory to Diagnose Depression (IDD) (a self-report scale to diagnose major depressive disorder). J Consult Clin Psychol. 1987;55:55–59
  11. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington (DC): American Psychiatric Association
  12. Seeff LB, Hoofnagle JH. National Institutes of Health Consensus Development Conference (management of hepatitis C: 2002). Hepatology. 2002;36(5 Suppl 1):S1–2
  13. Goldsmith RJ, Mindrum G, Myaing M. Psychiatric assessment of patients with hepatitis C virus before initiating interferon treatment. Psychiatr Ann. 2003;33:369–376

PII: S0163-8343(04)00017-9

doi: 10.1016/j.genhosppsych.2004.01.003

General Hospital Psychiatry
Volume 26, Issue 3 , Pages 237-240 , May 2004

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