General Hospital Psychiatry
Volume 26, Issue 3 , Pages 210-218 , May 2004

Description of a clinical pharmacist intervention administered to primary care patients with depression

  • Kathleen M Bungay, Pharm.D.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • Tufts University School of Medicine, Boston, MA, USA
    • Department of Psychiatry, Tufts-New England Medical Center, Boston, MA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-617-636-3292; fax: +1-617-636-8351.
    • ,
  • David A Adler, M.D.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • Tufts University School of Medicine, Boston, MA, USA
    • Department of Psychiatry, Tufts-New England Medical Center, Boston, MA, USA
    • ,
  • William H Rogers, Ph.D.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • ,
  • Christopher McCoy, Pharm.D.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • ,
  • Maryann Kaszuba, Pharm.D.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • ,
  • Stacey Supran, M.Sc.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • ,
  • Yu Pei, M.P.A.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • ,
  • Diane J Cynn, B.A.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • ,
  • Ira B Wilson, M.D., M.Sc.

      Affiliations

    • The Health Institute, The Institute for Clinical Research and Health Policy Studies, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street, Box 345, Boston, MA 02111, USA
    • Tufts University School of Medicine, Boston, MA, USA

Received 8 October 2003 ,Accepted 7 January 2004.

References 

  1. US Department of Health and Human Services. Mental health: a report of the surgeon general. Rockville (MD): US Department of Health and Human Services, Substance Abuse and Mental Health Services Administration, Center for Mental Health Services, National Institutes of Health, National Institute of Mental Health, 1999
  2. Depression Guidelines Panel. Depression in primary care: volume 1. Detection and diagnosis. Volume 2. Treatment of major depression. Clinical practice guidelines number 5. Rockville (MD): US Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, 1993
  3. Rost K, Nutting P, Smith J, Werner J, Duan N. Improving depression outcomes in community primary care practice (a randomized trial of the quest intervention). J Gen Intern Med. 2001;16:143–149
  4. Katzelnick DJ, Simon GE, Pearson SD, et al.  Randomized trial of a depression management program in high utilizers of medical care. Arch Fam Med. 2000;9:345–351
  5. Schulberg HC, Block MR, Madonia MJ, et al.  Treating major depression in primary care practice. Eight-month clinical outcomes. Arch Gen Psychiatry. 1996;53:913–919
  6. Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD (the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire). JAMA. 1999;282:1737–1744
  7. Wells KB, Sherbourne C, Schoenbaum M, Duan N, et al.  Impact of disseminating quality improvement programs for depression in managed primary care (a randomized controlled trial). JAMA. 2000;283:212–220
  8. Wells KB. The design of Partners in Care (evaluating the cost-effectiveness of improving care for depression in primary care). Soc Psychiatry Psychiatr Epidemiol. 1999;34:20–29
  9. Simon GE, VonKorff M, Rutter C, Wagner E. Randomised trial of monitoring, feedback, and management of care by telephone to improve treatment of depression in primary care. Br Med J. 2000;320:550–554
  10. Hunkeler EM, Meresman JF, Hargreaves WA, et al.  Efficacy of nurse telehealth care and peer support in augmenting treatment of depression in primary care. Arch Fam Med. 2000;9:700–708
  11. Katon W, Robinson P, Von Korff M, et al.  A multifaceted intervention to improve treatment of depression in primary care. Arch Gen Psychiatry. 1996;53:924–932
  12. Katon W, Von Korff M, Lin E, et al.  Collaborative management to achieve treatment guidelines. Impact on depression in primary care. JAMA. 1995;273:1026–1031
  13. Katon W, Von Korff M, Lin E, et al.  Stepped collaborative care for primary care patients with persistent symptoms of depression (a randomized trial). Arch Gen Psychiatry. 1999;56:1109–1115
  14. Schoenbaum M, Unutzer J, Sherbourne C, et al.  Cost-effectiveness of practice-initiated quality improvement for depression (results of a randomized controlled trial). JAMA. 2001;286:1325–1330
  15. 15th Biennial International Conference on Mental Health Services Research. Evidence in mental health services research, what types, how much and then what? Washington (DC), 2002
  16. Ablon JS, Jones EE. Validity of controlled clinical trials of psychotherapy (findings from the NIMH treatment of depression collaborative research program). Am J Psychiatry. 2002;159:775–783
  17. Rogers WH, Wilson IB, Bungay KM, Cynn DJ, Adler DA. Assessing the performance of a new depression screener for primary care (PC-SAD©). J Clin Epidemiol. 2002;55:164–175
  18. Adler DA, Bungay KM, Wilson IB, et al. The impact of a pharmacist intervention on 6-month outcomes depressed primary care patients. Gen Hosp Psychiatry 2004;26:199–209
  19. Bungay KM, Adler DA. Assessing and improving depressed patients' medication taking behaviors: a clinical pharmacists' guide. Unpublished manuscript. Available from authors: kbungay@tufts-nemc.org
  20. Tietze KJ. Taking medication histories. In:  Roche J editors. Clinical skills for pharmacists (a patient-focused approach). St. Louis (MO): Mosby-Year Book, Inc; 1997;p. 39–55
  21. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979;134:382–389
  22. Miller WR, Rollnick S. Motivational interviewing (preparing people to change addictive behavior). New York: Guilford Publications Inc; 1991;
  23. Prochaska JO, DiClemente CC. Stages of change in the modification of problem behaviors. Prog Behav Modif. 1992;28:183–218
  24. Prochaska JO, DiClemente CC. The transtheoretical approach (crossing traditional boundaries of therapy). Florence (KY): Brooks/Cole; 1984;
  25. Prochaska JO, Velicer WF, Rossi JS, et al.  Stages of change and decisional balance for 12 problems behaviors. Health Psychol. 1994;13:39–46
  26. StataCorp . Stata reference manual release 7. College Station (TX): Stata Press; 2001;
  27. Wilkinson G, Allen P, Marshall E, Walker J, Browne W, Mann AH. The role of the practice nurse in the management of depression in general practice (treatment adherence to antidepressant medication). Psychol Med. 1993;23:229–237
  28. Nutting PA, Rost K, Dickinson M, et al.  Barriers to initiating depression treatment in primary care practice. J Gen Intern Med. 2002;17:103–111
  29. Ziegler DK, Mosier MC, Buenaver M, Okuyemi K. How much information about adverse effects of medication do patients want from physicians?. Arch Intern Med. 2001;161:706–713
  30. Bates DW, Boyle DL, Vander Vliet MB, Schneider J, Leape L. Relationship between medication errors and adverse drug events. J Gen Intern Med. 1995;10:199–205
  31. Wagner EH, Austin BT, Von Korff M. Organizing care for patients with chronic illness. Milbank Q. 1996;74:511–544
  32. Finley PR. Psychiatric pharmacists-indispensable members of mental healthcare teams. NAMI Advocate 2002;13–4
  33. Hammond RW, Schwartz AH, Campbell MJ, et al.  Collaborative drug therapy management by pharmacists—2003. Pharmacotherapy. 2003;23:1210–1225
  34. Finley PR, Crismon ML, Rush AJ. Evaluating the impact of pharmacists in mental health (a systematic review). Pharmacotherapy. 2003;23:1634–1644
  35. Finley PR, Rens HR, Pont JT, et al.  Impact of a collaborative care model on depression in a primary care setting (a randomized controlled trial). Pharmacotherapy. 2003;23:1175–1185
  36. Boudreau DM, Capoccia KL, Sullivan SD, et al.  Collaborative care model to improve outcomes in major depression. Ann Pharmacother. 2002;36:585–591

PII: S0163-8343(04)00018-0

doi: 10.1016/j.genhosppsych.2004.01.004

General Hospital Psychiatry
Volume 26, Issue 3 , Pages 210-218 , May 2004

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