General Hospital Psychiatry
Volume 27, Issue 5 , Pages 329-337, September 2005

A cognitive therapy conceptualization of panic disorder exacerbated by interferon treatment

  • Guy A. Farber, M.D.

      Affiliations

    • Department of Consultation and Liaison Psychiatry, Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA
    • Corresponding Author InformationCorresponding author. Tel.: +44 718 268 7289; fax: +44 718 544 1735.
    • ,
  • Tomer Levin, M.D.

      Affiliations

    • Department of Consultation and Liaison Psychiatry, Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA
    • ,
  • Craig A. White, Clin.Psy.D., Ph.D.

      Affiliations

    • Consulting and Clinical Psychology Services, NHS Ayrshire and Arran, Ayrshire Central Hospital, Irvine, KA12 8SS Scotland, UK
    • Faculty of Medicine, University of Glasgow, G12 0XH Scotland, UK

Received 18 February 2005; accepted 23 May 2005.

Abstract 

This case conference presents a patient with von Willebrand disease, receiving year-long interferon treatment for hepatitis C. She was referred to C-L Psychiatry following a severe exacerbation of panic disorder. Our guest interviewer is Dr. Craig White, a Scottish cognitive therapist. The subsequent discussion outlines the treatment challenges of panic disorder that occurs when a patient is receiving interferon. A literature review evaluates psychological effects of interferon and biological mechanisms by which interferon may exacerbate anxiety and depression. A cognitive therapy conceptualization of interferon-induced exacerbation of panic disorder is proposed.

Keywords: Panic disorder, Anxiety, Interferon, Hepatitis C, Cognitive therapy

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PII: S0163-8343(05)00074-5

doi:10.1016/j.genhosppsych.2005.05.012

General Hospital Psychiatry
Volume 27, Issue 5 , Pages 329-337, September 2005

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