General Hospital Psychiatry
Volume 28, Issue 5 , Pages 396-402 , September 2006

Effect of depression on all-cause mortality in adults with cancer and differential effects by cancer site

  • Adedayo A. Onitilo, M.D., M.S.C.R.

      Affiliations

    • Department of Hematology/Oncology, Marshfield Clinic-Wausau Center, Wausau, WI 54401, USA
  • ,
  • Paul J. Nietert, Ph.D.

      Affiliations

    • Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA
  • ,
  • Leonard E. Egede, M.D., M.S.

      Affiliations

    • Division of General Internal Medicine, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
    • Charleston VA TREP, Ralph H. Johnson VA Medical Center, Charleston, SC 29401, USA
    • Corresponding Author InformationCorresponding author. Center for Health Disparities Research, Medical University of South Carolina, Charleston, SC 29425, USA. Tel.: +1 843 792 2969; fax: +1 843 876 1201.

Received 21 February 2006 ,Accepted 18 May 2006.

References 

  1. Stewart SL, King JB, Thompson TD, Friedman C, Wingo PA. Cancer mortality surveillance — United States, 1990–2000. MMWR Surveill Summ. 2004;53:1–108
  2. Centers for Disease Control and Prevention . Breast cancer incidence and mortality — United States, 1992. MMWR Morb Mortal Wkly Rep. 1996;451:833–837
  3. Jemal A, Kulldorff M, Devesa SS, Hayes RB, Fraumeni JF. A geographic analysis of prostate cancer mortality in the United States, 1970–89. Int J Cancer. 2002;101:168–174
  4. Centers for Disease Control and Prevention . Recent trends in mortality rates for four major cancers, by sex and race/ethnicity — United States, 1990–1998. MMWR Morb Mortal Wkly Rep. 2002;51:49–53
  5. Clegg LX, Li FP, Hankey BF, Chu K, Edwards BK. Cancer survival among US whites and minorities: a SEER (Surveillance, Epidemiology, and End Results) program population-based study. Arch Intern Med. 2002;162:1985–1993
  6. Centers for Disease Control and Prevention . Cancer mortality among American Indians and Alaska Natives — United States, 1994–1998. MMWR Morb Mortal Wkly Rep. 2003;52:704–707
  7. Weir HK, Thun MJ, Hankey BF, Ries LA, Howe HL, Wingo PA, et al. Annual report to the nation on the status of cancer, 1975–2000, featuring the uses of surveillance data for cancer prevention and control. J Natl Cancer Inst. 2003;95:1276–1299
  8. Chu KC, Lamar CA, Freeman HP. Racial disparities in breast carcinoma survival rates: separating factors that affect diagnosis from factors that affect treatment. Cancer. 2003;97:2853–2860
  9. Cobb N, Paisano RE. Patterns of cancer mortality among Native Americans. Cancer. 1998;83:2377–2383
  10. Hershman D, Weinberg M, Rosner Z, Alexis K, Tiersten A, Grann VR, et al. Ethnic neutropenia and treatment delay in African American women undergoing chemotherapy for early-stage breast cancer. J Natl Cancer Inst. 2003;95:1545–1548
  11. Kowal SJ. Emotions as a cause of cancer; 18th and 19th century contributions. Psychoanal Rev. 1955;42:217–227
  12. Massie MJ. Prevalence of depression in patients with cancer. J Natl Cancer Inst Monogr. 2004;32:57–71
  13. Polsky D, Doshi JA, Marcus S, Oslin D, Rothbard A, Thomas N, et al. Long-term risk for depressive symptoms after a medical diagnosis. Arch Intern Med. 2005;165:1260–1266
  14. Fras I, Litin EM, Pearson JS. Comparison of psychiatric symptoms in carcinoma of the pancreas with those in some other intra-abdominal neoplasms. Am J Psychiatry. 1967;123:1553–1562
  15. Joffe RT, Rubinow DR, Denicoff KD, Maher M, Sindelar WF. Depression and carcinoma of the pancreas. Gen Hosp Psychiatry. 1986;8:241–245
  16. Holland JC, Korzun AH, Tross S, Silberfarb P, Perry M, Comis R, et al. Comparative psychological disturbance in patients with pancreatic and gastric cancer. Am J Psychiatry. 1986;143:982–986
  17. Morton RP, Davies AD, Baker J, Baker GA, Stell PM. Quality of life in treated head and neck cancer patients: a preliminary report. Clin Otolaryngol. 1984;9:181–185
  18. Davies AD, Davies C, Delpo MC. Depression and anxiety in patients undergoing diagnostic investigations for head and neck cancers. Br J Psychiatry. 1986;149:491–493
  19. Maguire GP, Lee EG, Bevington DJ, Kuchemann CS, Crabtree RJ, Cornell CE. Psychiatric problems in the first year after mastectomy. Br Med J. 1978;1:963–965
  20. Silberfarb PM, Philibert D, Levine PM. Psychosocial aspects of neoplastic disease: II. Affective and cognitive effects of chemotherapy in cancer patients. Am J Psychiatry. 1980;137:597–601
  21. Farber JM, Weinerman BH, Kuypers JA. Psychosocial distress in oncology outpatients. J Psychosoc Oncol. 1984;2:109–118
  22. Grandi S, et al. Major depression associated with mastectomy. Med Sci Res. 1987;15:283–284
  23. Fallowfield LJ, Hall A, Maguire GP, Baum M. Psychological outcomes of different treatment policies in women with early breast cancer outside a clinical trial. BMJ. 1990;301:575–580
  24. Koenig R, Levin SM, Brennan MJ. The emotional status of cancer patients as measured by a psychological test. J Chronic Dis. 1967;20:923–930
  25. Evans DL, McCartney CF, Nemeroff CB, Raft D, Quade D, Golden RN, et al. Depression in women treated for gynecological cancer: clinical and neuroendocrine assessment. Am J Psychiatry. 1986;143:447–452
  26. Devlen J, Maguire P, Phillips P, Crowther D, Chambers H. Psychological problems associated with diagnosis and treatment of lymphomas: I. Retrospective study. Br Med J (Clin Res Ed). 1987;295:953–954
  27. McDaniel JS, Musselman DL, Porter MR, Reed DA, Nemeroff CB. Depression in patients with cancer. Diagnosis, biology, and treatment. Arch Gen Psychiatry. 1995;52:89–99
  28. Spiegel D, Giese-Davis J. Depression and cancer: mechanisms and disease progression. Biol Psychiatry. 2003;54:269–282
  29. LeShan L. Cancer mortality rate. Some statistical evidence of the effect of psychological factors. Arch Gen Psychiatry. 1962;6:333–335
  30. LeShan L, Worthington RE. Some recurrent life history patterns observed in patients with malignant disease. J Nerv Ment Dis. 1956;124:460–465
  31. LeShan L, Worthington RE. Personality as factor in the pathogenesis of cancer: a review of the literature. Br J Med Psychol. 1956;29:49–56
  32. Newport DJ, Nemeroff CB. Assessment and treatment of depression in the cancer patient. J Psychosom Res. 1998;45:215–237
  33. Pirl WF, Roth AJ. Diagnosis and treatment of depression in cancer patients. Oncology (Williston Park, N.Y.). 1999;13:1293–1301
  34. Dunlop DD, Lyons JS, Manheim LM, Song J, Chang RW. Arthritis and heart disease as risk factors for major depression: the role of functional limitation. Med Care. 2004;42:502–511
  35. Mossey JM, Gallagher RM. The longitudinal occurrence and impact of comorbid chronic pain and chronic depression over two years in continuing care retirement community residents. Pain Med. 2004;5:335–348
  36. Aukst-Margetić B, Jakovljević M, Margetić B, Bišćan M, Šamija M. Religiosity, depression and pain in patients with breast cancer. Gen Hosp Psychiatry. 2005;27:250–255
  37. Zonderman AB, Costa PT, McCrae RR. Depression as a risk for cancer morbidity and mortality in a nationally representative sample. JAMA. 1989;262:1191–1195
  38. Hjerl K, Andersen EW, Keiding N, Mouridsen HT, Mortensen PB, Jorgensen T. Depression as a prognostic factor for breast cancer mortality. Psychosomatics. 2003;44:24–30
  39. National Center for Health Statistics . Plan and operation of the Health and Nutrition Examination Survey, United States, 1971–1973. National Center for Health Statistics. Vital Health Stat. 1973;1(10):
  40. Cohen BB, Barbano HE, Cox CS, Feldman JJ, Finucane FF, Kleinman JC, et al. Plan and operation of the NHANES 1 Epidemiologic Follow-up Study 1982–84. National Center for Health Statistics. Vital Health Stat. 1987;1(22):1–142
  41. Cox CS, Mussolino ME, Rothwell ST, Lane MA, Golden CD, Madans JH, et al. Plan and operation of the NHANES 1 Epidemiologic Follow-up Study 1992. National Center for Health Statistics. Vital Health Stat. 1997;1(35):1–231
  42. Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385–401
  43. Roberts RE, Vernon SW. The Center for Epidemiologic Studies Depression Scale: its use in a community sample. Am J Psychiatry. 1983;140(1):41–46
  44. Knight RG, Williams S, McGee R, Olaman S. Psychometric properties of the Centre for Epidemiologic Studies Depression Scale (CES-D) in a sample of women in middle life. Behav Res Ther. 1997;35(4):373–380
  45. Lyness JM, Noel TK, Cox C, King DA, Conwell Y, Caine ED. Screening for depression in elderly primary care patients. A comparison of the Center for Epidemiologic Studies — Depression Scale and the Geriatric Depression Scale. Arch Intern Med. 1997;157(4):449–454
  46. Stampfer MJ, Willett WC, Speizer FE, et al. Test of the National Death Index. Am J Epidemiol. 1984;119(5):837–839
  47. Rich-Edwards JW, Corsano KA, Stampfer MJ. Test of the National Death Index and Equifax Nationwide Death Search. Am J Epidemiol. 1994;140(11):1016–1019
  48. SAS [software program] Version 9.0. Cary (NC): SAS Institute, Inc., 2002.
  49. SUDAAN [computer program for statistical analysis of correlated data] Release 8.0. Research Triangle Park (NC): Research Triangle Institute, 2001.
  50. Bleiker EM, van der Ploeg HM, Hendriks JH, Ader HJ. Personality factors and breast cancer development: a prospective longitudinal study. J Natl Cancer Inst. 1996;88:1478–1482
  51. Kaplan GA, Reynolds P. Depression and cancer mortality and morbidity: prospective evidence from the Alameda county study. J Behav Med. 1988;11:1–13
  52. Teno JM, Harrell FEJ, Knaus W, Phillips RS, Wu AW, Connors A, et al. Prediction of survival for older hospitalized patients: the HELP survival model. Hospitalized Elderly Longitudinal Project. J Am Geriatr Soc. 2000;48(Suppl 5):S16–S24
  53. Tross S, Herndon J, Korzun A, Kornblith AB, Cella DF, Holland JF, et al. Psychological symptoms and disease-free and overall survival in women with stage II breast cancer. Cancer and Leukemia Group B. J Natl Cancer Inst. 1996;88:661–667
  54. Shekelle RB, Raynor W, Ostfeld AM, Garron DC, Bieliauskas LA, Liu SC, et al. Psychological depression and 17-year risk of death from cancer. Psychosom Med. 1981;43:117–125
  55. Loberiza FR, Rizzo JD, Bredeson CN, Antin JH, Horowitz MM, Weeks JC, et al. Association of depressive syndrome and early deaths among patients after stem-cell transplantation for malignant diseases. J Clin Oncol. 2002;20:2118–2126
  56. Stommel M, Given BA, Given CW. Depression and functional status as predictors of death among cancer patients. Cancer. 2002;94:2719–2727
  57. Herrmann C, Brand-Driehorst S, Kaminsky B, Leibling E, Staats H, Ruger U. Diagnostic groups and depressed mood as predictors of 22-month mortality in medical inpatients. Psychosom Med. 1998;60:570–577
  58. Watson M, Haviland JS, Greer S, Davidson J, Bliss JM. Influence of psychological response on survival in breast cancer: a population-based cohort study. Lancet. 1999;354:1331–1336
  59. Spiegel D, Giese-Davis J. Depression and cancer: mechanisms and disease progression. Biol Psychiatry. 2003;54(3):269–282
  60. Edwards WS, Winn DM, Kurlantzick V, Sheridan S, Berk ML, Retchin S, et al. Evaluation of national health interview survey diagnostic reporting. National Center for Health Statistics. Vital Health Stat. 1994;120:1–116

PII: S0163-8343(06)00091-0

doi: 10.1016/j.genhosppsych.2006.05.006

General Hospital Psychiatry
Volume 28, Issue 5 , Pages 396-402 , September 2006