General Hospital Psychiatry
Volume 31, Issue 6 , Pages 586-588, November 2009

Schizophrenia-like psychotic episode precipitated by cobalamin deficiency

Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

Received 10 November 2008; accepted 17 February 2009. published online 31 March 2009.

Abstract 

Although cobalamin deficiency is widely known and usually presents with hematologic and neuropsychiatric manifestations, the psychiatric symptoms are not usually the predominant manifestation. We describe a young single male vegetarian who developed a cobalamin-induced psychotic episode without preceding neurologic manifestations and without any hematologic symptoms. He recovered after a short course of antipsychotics and oral cobalamin supplementation and remained asymptomatic and functionally independent at 1 year of follow-up.

Keywords: Cobalamin deficiency, Psychosis

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PII: S0163-8343(09)00017-6

doi:10.1016/j.genhosppsych.2009.02.003

General Hospital Psychiatry
Volume 31, Issue 6 , Pages 586-588, November 2009