General Hospital Psychiatry
Volume 32, Issue 3 , Pages 341.e1-341.e2, May 2010

Repeated angioedema following administration of venlafaxine and mirtazapine☆

Department of Psychiatry, Tri-Service General Hospital, Taipei 114, Taiwan

Received 10 January 2009; accepted 4 March 2009. published online 16 April 2009.

Abstract 

We report a rare case of a 48-year-old female who presented with bilateral lower-leg swelling due to a medication-induced angioedema resulting from the use of two common classes of antidepressants, venlafaxine and mirtazapine. Although the mechanisms by which the antidepressants achieve these effects are not understood, the recent recognition of a novel antidepressant-dependent form of angioedema may offer important insights into the mechanisms by which the antidepressants exert their effects.

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☆ No financial support was received for this report. This article has not been submitted either completely or in part to another journal.

PII: S0163-8343(09)00049-8

doi:10.1016/j.genhosppsych.2009.03.004

General Hospital Psychiatry
Volume 32, Issue 3 , Pages 341.e1-341.e2, May 2010

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