General Hospital Psychiatry
Volume 32, Issue 4 , Pages 377-379 , July 2010

Relationship between antidepressant medication possession and treatment response

  • John C. Fortney, Ph.D.

      Affiliations

    • VA South Central Mental Illness Education and Clinic Center (MIRECC), Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA
    • VA Health Services Research and Development (HRS&D), Center for Mental Health and Outcomes Research, Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA
    • Division of Health Services Research, Department of Psychiatry, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    • Corresponding Author InformationCorresponding author. VA HSR&D CeMHOR (152/NLR), North Little Rock, AR 72114, USA. Tel.: +1 501 257 1726.
    • ,
  • Jeffrey M. Pyne, M.D.

      Affiliations

    • VA South Central Mental Illness Education and Clinic Center (MIRECC), Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA
    • VA Health Services Research and Development (HRS&D), Center for Mental Health and Outcomes Research, Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA
    • Division of Health Services Research, Department of Psychiatry, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    • ,
  • Mark J. Edlund, M.D., Ph.D.

      Affiliations

    • Division of Health Services Research, Department of Psychiatry, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    • ,
  • Dinesh Mittal, M.D.

      Affiliations

    • VA South Central Mental Illness Education and Clinic Center (MIRECC), Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA
    • VA Health Services Research and Development (HRS&D), Center for Mental Health and Outcomes Research, Central Arkansas Veterans Healthcare System, North Little Rock, AR, USA
    • Division of Health Services Research, Department of Psychiatry, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Received 30 October 2009 ,Accepted 20 March 2010.

References 

  1. Alegria M, Frank R, McGuire T. Managed care and systems cost-effectiveness. Treatment for depression. Med Care. 2005;43(12):1225–1233
  2. Frank RG, McGuire TG, Normand ST, Goldman HH. The value of mental health care at the system level: the case of treating depression. Health Aff. 1999;18(5):71–88
  3. Fortney JC, Pyne JM, Edlund MJ, et al. Design and implementation of the Telemedicine-Enhanced Antidepressant Management Study. Gen Hosp Psychiatry. 2006;28(1):18–26
  4. Derogatis LR, Lipman RS, Rickels K, Uhlenhuth EH, Covi L. The Hopkins Symptom Checklist (HSCL): a measure of primary symptom dimensions. Pharmacopsychiatry. 1974;7:79–110
  5. Fortney JC, Pyne JM, Edlund MJ, et al. Reasons for antidepressant non-adherence among veterans treated in primary care clinics. J Clin Psychiatry [in press].
  6. Simon GE, Lin EHB, Katon W, et al. Outcomes of “inadequate” antidepressant treatment. J Gen Intern Med. 1995;10(12):663–670
  7. Lecrubier Y, Sheehan DV, Weiller E, et al. The Mini International Neuropsychiatric Interview (MINI). A short diagnostic structured interview: reliability and validity according to the CIDI. Eur Psychiatry. 1997;12(5):224–231
  8. Valenstein M, Austin K, Khanuja K, McCarthy JF. Specialty care for veterans with depression in the VHA: 2002 National Registry for Depression (NARDEP) Report. Ann Arbor (MI): Serious Mental Illness Treatment Research and Evaluation Center; 2003;

☆ Human subjects approval: The study was approved by the Research and Development Committees of the Central Arkansas Veterans Healthcare System in Little Rock, AR; the Overton Brooks VA Medical Center in Shreveport, LA; and the G.V. (Sonny) Montgomery VA Medical Center in Jackson, MS; and their affiliated institutional review boards at the University of Arkansas for Medical Sciences and the University of Louisiana Health Sciences Center at Shreveport.

☆☆ This research was supported by VA IIR 00-078-3 grant to Dr. Fortney, VA NPI-01-006-1 grant to Dr. Pyne, the VA HSR&D Center for Mental Health and Outcomes Research, and the VA South Central Mental Illness Research Education and Clinical Center. Drs. Pyne and Edlund were supported by VA HSR&D Research Career Awards. Dr. Mittal was supported by the VISN 16 South Central Network Research/Career Development Grant Program and VA South Central Mental Illness Research Education and Clinical Center.

PII: S0163-8343(10)00058-7

doi: 10.1016/j.genhosppsych.2010.03.008

General Hospital Psychiatry
Volume 32, Issue 4 , Pages 377-379 , July 2010

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